Description
Modafinil (Provigil): Uses, Dosage, and Safety Guide
Modafinil 200 mg, sold under Provigil, is a prescription medication used to promote wakefulness in individuals suffering from excessive daytime sleepiness. It is most commonly prescribed for sleep disorders like narcolepsy, obstructive sleep apnea (OSA), and shift work sleep disorder (SWSD).
What Is Modafinil Used For?
Modafinil helps people stay awake and alert during the day. It is FDA-approved for:
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Narcolepsy – a condition that causes sudden and uncontrollable episodes of sleep
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Obstructive Sleep Apnea (OSA) – used alongside CPAP therapy to reduce residual sleepiness
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Shift Work Sleep Disorder – improves alertness in people working overnight or rotating shifts
How Does Modafinil Work?
Modafinil is classified as a wakefulness-promoting agent. While its exact mechanism isn’t fully understood, it’s believed to work by stimulating specific areas of the brain that control wakefulness and attention.
Unlike traditional stimulants, Modafinil is less likely to cause jitteriness or a crash and has a low risk of addiction when used as directed.
Available Dosage Forms
Modafinil comes in tablet form and is typically available in:
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100 mg tablets
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200 mg tablets
The standard dose for most adults is 200 mg once daily, either in the morning or about an hour before the start of a night shift.
Important Usage Notes
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For OSA patients, Modafinil treats sleepiness, not the underlying condition. Continue using prescribed breathing devices, such as a CPAP machine.
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Take only as prescribed: Modafinil is a Schedule IV controlled substance due to the rare potential for misuse.
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Store securely: Keep in a safe place away from children and others.
Possible Side Effects of Modafinil
While many people tolerate Modafinil well, some may experience side effects. Common ones include:
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Headache
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Nausea
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Nervousness or anxiety
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Dry mouth
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Insomnia
More serious side effects (seek medical attention immediately):
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Allergic reactions or skin rashes (e.g., Stevens-Johnson Syndrome)
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Mental health symptoms like mood changes, mania, or suicidal thoughts
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Heart problems, including chest pain or irregular heartbeat
Final Thoughts
Modafinil (Provigil) is a well-established option for treating excessive sleepiness linked to various sleep disorders. When used responsibly under medical supervision, it can dramatically improve alertness, daily function, and quality of life.
Always talk to your healthcare provider before starting Modafinil, and follow your prescribed treatment plan—especially if using it alongside CPAP therapy for sleep apnea.

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